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KMID : 0357919850190040449
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Korean Journal of Pathology
1985 Volume.19 No. 4 p.449 ~ p.452
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Composite Carcinoma - Carcinoid Tumor of Stomach -Report of a case-
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Abstract
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The concurrence of typical carcinoid admixed with adenocarcinoma of the
gastrointestinal tract is a well known but unusual phenomenom that has been reported
In the esophagus, stomach, gall bladder, colon and appendix.
The amine precursor uptake and decarboxylation(APUD) concept included the idea that
neuroendocrine cells of the gastrointestinal tract were derided from the neural crest by a
process of migration during embryogenesis.
However the intimate admixture of cells which have morphologic and
immunocytochemical properties of both carcinoid tumors and adenocarcinoma suggests
that these tumors are derived from a multipotential stem cell showing bidirectional
differentiation rather than from unrelated cell lines.
The term composite carcinoma-carcinoid tumor is therefore an appropriate designation
for these neoplasms.
We report a case of composite carcinoma-carcinoid tumor of the stomach in a 38
year-old female with brief review of literature.
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